Catalogue Number:A536010
Chemical Name:Aliskiren Carboxylic Acid
Synonyms:3-[[(2S,4S,5S,7S)-5-Amino-4-hydroxy-7-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-8-methyl-2-(1-methylethyl)-1-oxononyl]amino]-2,2-dimethyl-propanoic Acid
CAS Number:173400-13-0
Molecular Formula:C₃₀H₅₂N₂O₇
Molecular Weight:552.74
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Aliskiren Carboxylic Acid is an impurity of Aliskiren (A536000), an orally active, synthetic nonpeptide renin inhibitor. Antihypertensive.
References:Lefevre, G., et al.: J. Immunoassay, 21, 65 (2000); Allikments, K., et al.: Curr. Opin. Invest. Drugs, 3, 1479 (2002); Wood; J.M., et al.: Biochem. Biophys. Res. Commun., 308, 698 (2003); Grandman, A.H., et al.: Circulation, 111, 1012 (2005)
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