Catalogue Number:D245513
Chemical Name:(-)-2′-Deoxy-3′-oxa-4′-thiocytidine (Apricitabine)
Synonyms:2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-, (2R-cis)-; 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.; 4-Amino-1-[(2R,4R)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-2(1H)-pyrimidinone; (-)-2′-Deoxy-3′-oxa-4′-thiocytidine; (-)-BCH 10652; AVX 754; Apricitabine;BCH 10618; SPD 754
CAS Number:160707-69-7
Molecular Formula:C₈H₁₁N₃O₃S
Molecular Weight:229.25
Category:Building Blocks; Chiral Molecules;
Boiling Point
475-530°C
Applications:(-)-2′-Deoxy-3′-oxa-4′-thiocytidine (Apricitabine) is a drug that is used in the treatment of HIV aids. It as also been shown to be useful against lamivudine and zidovudine resistant virus strains
References:Sebastian M., et al.: Org. Proc. Res. & Dev., 265, 763-773 (2011) Ghosh, R., et al.: Expert Opin. Pharmacother., 12, 31-46 (2011)
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