Catalogue Number:B324000
Chemical Name:Betahistine Hydrochloride
Synonyms:N-(Methyl-d3)-2-pyridineethanamine Hydrochloride; 2-[2-(Methylamino)ethyl]pyridine Hydrochloride; [2-(2-Pyridyl)ethyl]methylamine Hydrochloride;
CAS Number:15430-48-5
Alternate CAS #
Dihydrochloride: 5579-84-0
Molecular Formula:C₈H₁₂N₂ • HCl
Appearance:Pale Yellow Solid
Melting Point:94-97°C
Molecular Weight:136.20 + 36.46
Storage:4°C, Hygroscopic
Solubility:DMSO (Slightly), Water (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Betahistine is most commonly used to treat the symptoms of Ménière’s disease and vertigo. Vasodilator.
References:Gilligan, P., et al.: J. Med. Chem., 43, 1641 (2000), Keller, P., et al.: Bioorg. Med. Chem., 8, 1213 (2000), Hauger, R., et al.: Pharmacol. Rev., 55, 21 (2003), Han, X., et al.: Bioorg. Med. Chem. Lett., 15, 3870 (2005),
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