Catalogue Number:B327070
Chemical Name:Betamethasone 17-Propionate 21-Mesylate
Synonyms:(11β,16β)-9-Fluoro-11-hydroxy-16-methyl-21-[(methylsulfonyl)oxy]-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione; 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-Methanesulfonate 17-Propionate; Clobetasol Propionate EP Impurity I
Impurity:Clobetasol Propionate EP Impurity I
CAS Number:15423-80-0
Molecular Formula:C₂₆H₃₅FO₈S
Appearance:Pale Yellow to Yellow Solid
Melting Point:>126°C (dec.)
Molecular Weight:526.61
Storage:-20°C
Solubility:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Very Slightly)
Stability
Hygroscopic
Category:Standards; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Betamethasone 17-Propionate 21-Mesylate (Clobetasol Propionate EP Impurity I) is the 21-mesylate analogue of Betamethasone 17-Acetate (B327015) with antiinflammatory activity.
References:Mitsukuchi, M. et al.: Chem. Pharm. Bull., 37, 3286 (1989);
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