CAS:148930-30-7|2’-O-(Benzyloxycarbonyl) Taxol

Catalogue Number:B287015
Chemical Name:2’-O-(Benzyloxycarbonyl) Taxol
Synonyms:7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.; 2′-(Benzyloxycarbonyl)taxol; [2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-β-(Benzoylamino)-α-[[(phenylmethoxy)carbonyl]oxy]benzenepropanoic Acid 6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; (αR,βS)-β-(Benzoylamino)-α-[[(phenylmethoxy)carbonyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester
CAS Number:148930-30-7
Molecular Formula:C₅₅H₅₇NO₁₆
Appearance:Off-White Solid
Molecular Weight:988.04
Solubility:Chloroform, DCM, Ethyl Acetate, Methanol
Category:Building Blocks; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2’-O-(Benzyloxycarbonyl) Taxol is an protected intermediate in the synthesis of Paclitaxel (P132500) related compound.
References:Lis, L.G., et al.: ACS. Med. Chem. Lett., 3, 745 (2012); Kumar, S.K., et al.: Bioorg. Med. Chem., 15, 4973 (2007); Ohtsu, H., et al.: Bioorg. Med. Chem., 11, 1851 (2003);
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