Catalogue Number:B286600
Chemical Name:4-Benzyloxy-3-methoxybenzoic Acid
Synonyms:4-Benzyloxy-3-methoxybenzoic Acid; NSC 16714; O-Benzylvanillic Acid
CAS Number:1486-53-9
Molecular Formula:C₁₅H₁₄O₄
Appearance:White to Off-White Solid
Melting Point:162 – 164°C
Molecular Weight:258.27
Storage:4°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Building Blocks; Miscellaneous;
Applications:4-Benzyloxy-3-methoxybenzoic Acid is used in the synthesis of Hsp90 inhibitors as EGCG analogues. Also used in the preparation of vanillates exhibiting cytostatic properties towards cancel cells resistant to pro-apoptotic stimuli.
References:Khandelwal, A. et al.: J. Org. Chem., 78, 7859 (2013); Lamoral-Theys, D. et al.: Bioorg. Med. Chem., 18, 3823 (2010);
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