CAS:147125-05-1|[1S-[1α[1S*(R*),3aR*,4E,7aS*],4β,6α]]- 4-[[4,6-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,3,4,5,6,7-hexahydro-2,2-dioxidobenzo[c]thien-1-yl]methylene]octahydro-β,7a-dimethyl-1H-indene-1-ethanol

Catalogue Number:B412740
Chemical Name:[1S-[1α[1S*(R*),3aR*,4E,7aS*],4β,6α]]- 4-[[4,6-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,3,4,5,6,7-hexahydro-2,2-dioxidobenzo[c]thien-1-yl]methylene]octahydro-β,7a-dimethyl-1H-indene-1-ethanol
Synonyms:[1S-[1α[1S*(R*),3aR*,4E,7aS*],4β,6α]]-4-[[4,6-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,3,4,5,6,7-hexahydrobenzo[c]thien-1-yl]methylene]octahydro-β,7a-dimethyl-1H-indene-1-ethanol; Benzo[c]thiophene 1H-Indene-1-ethanol Deriv.;
CAS Number:147125-05-1
Molecular Formula:C₃₄H₆₂O₅SSi₂
Molecular Weight:639.09
Category:Standards; Vitamin Derivatives; Vitamin D Derivatives;
Applications:[1S-[1α[1S*(R*),3aR*,4E,7aS*],4β,6α]]- 4-[[4,6-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,3,4,5,6,7-hexahydro-2,2-dioxidobenzo[c]thien-1-yl]methylene]octahydro-β,7a-dimethyl-1H-indene-1-ethanol is an intermediate used in the synthesis of ZK 159222 (Z485800), which is a vitamin D receptor antagonist. It is a derivative of Vitamin D3 (V676045).
References:Mizwicki, M., et al.: J. Bio. Chem., 284, 36292 (2009); Ochiai, E., et al.: Mol. Endocrinol., 19, 1147 (2005)
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