CAS:145354-81-0|(2S,4S)-2-[(Benzoyloxy)methyl]-1,3-dioxolane-4-carboxylic Acid

Catalogue Number:B315430
Chemical Name:(2S,4S)-2-[(Benzoyloxy)methyl]-1,3-dioxolane-4-carboxylic Acid
Synonyms:(2S-cis)-2-[(Benzoyloxy)methyl]-1,3-dioxolane-4-carboxylic Acid;
CAS Number:145354-81-0
Molecular Formula:C₁₂H₁₂O₆
Molecular Weight:252.22
Category:Building Blocks; Carbohydrates; Miscellaneous;
Applications:(2S,4S)-2-[(Benzoyloxy)methyl]-1,3-dioxolane-4-carboxylic Acid is an intermediate used in the synthesis of Troxacitabine (T805580), which is a nucleoside analogue with potential anticancer activity. Troxacitabine have been studied in patients with refractory lymphoproliferative diseases.
References:Robak, T., et al.: Curr. Med. Chem., 18, 638 (2011); Kornblau, S.M., et al.: Clin. Cancer. Res., 16, 3721 (2010);
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