Catalogue Number:C987290
Chemical Name:Trans-1,2-cyclohexanedicarboxylic Anhydride
Synonyms:Trans-hexahydro-1,3-isobenzofurandione; DL-trans-1,2-cyclohexanedicarboxylic Anhydride; Rel-(3aS,7aS)-hexahydroisobenzofuran-1,3-dione; Trans-1,2-cyclohexanedicarboxylic Anhydride; Trans-cyclohexane-1,2-dicarboxylic Acid Anhydride; Trans-hexahydrophthalic Anhydride
CAS Number:14166-21-3
Molecular Formula:C₈H₁₀O₃
Appearance:White to Off-White Solid
Melting Point:141 – 145°C
Molecular Weight:154.16
Storage:20°C
Solubility:Acetone (Sparingly), Chloroform (Slightly), DMSO (Slightly)
Stability
Moisture Sensitive
Category:Building Blocks; Monomers;
Applications:Trans-1,2-cyclohexanedicarboxylic anhydride can be used as a reagent to prepare hepatitis C virus (HCV) and granzyme B (indoline derivatives) inhibitors. It has also been employed in studies relating to the development of protein kinase C inhibitors.
References:Yang, Z., et al.: PCT Int. Appl. WO 2015124063 A1 20150827 (2015); Cameron, D. R. PCT Int. Appl. WO 2014153666 A1 20141002 (2014); Cameron, D. R. PCT Int. Appl. WO 2014153666 A1 20141002 (2014); Lampe, J. W., et al.: J. Med. Chem 45, 2624
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