CAS:1370438-57-5|(1R,​3R)​-1-​(1,​3-​Benzodioxol-​5-​yl)​-​2,​3,​4,​9-​tetrahydro-1H-​pyrido[3,​4-​b]​indole-​3-​carboxamide

Catalogue Number:B199995
Chemical Name:(1R,​3R)​-1-​(1,​3-​Benzodioxol-​5-​yl)​-​2,​3,​4,​9-​tetrahydro-1H-​pyrido[3,​4-​b]​indole-​3-​carboxamide
Synonyms:Tadalafil Amide Impurity:CAS Number:1370438-57-5
Molecular Formula:C₁₉H₁₇N₃O₃
Molecular Weight:335.36
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(1R,​3R)​-1-​(1,​3-​Benzodioxol-​5-​yl)​-​2,​3,​4,​9-​tetrahydro-1H-​pyrido[3,​4-​b]​indole-​3-​carboxamide is an analogue of Tadalafil (T004500), which is a human PDE5 inhibitor. (1R,​3R)​-1-​(1,​3-​Benzodioxol-​5-​yl)​-​2,​3,​4,​9-​tetrahydro-1H-​pyrido[3,​4-​b]​indole-​3-​carboxamide is a weak inhibitor of TbrPDEB1.
References:Ochiana, S.O., et al.: Bioorg. Med. Chem. Lett., 22, 2582 (2012)
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