Catalogue Number:D288140
Chemical Name:3-Descyano-3-((hydroxyimino)methyl) Febuxostat
Synonyms:2-[3-[(Hydroxyimino)methyl]-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid
CAS Number:1350352-70-3
Molecular Formula:C₁₆H₁₈N₂O₄S
Appearance:White Solid
Melting Point:>215°C (dec.)
Molecular Weight:334.39
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3-Descyano-3-((hydroxyimino)methyl) Febuxostat is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor that is used for treating hyperuricemia and chronic gout.
References:Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)
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