Catalogue Number:B208550
Chemical Name:(2R,3S)-N-Benzoyl-3-phenyl Isoserine
Synonyms:(αR,βS)-β-(Benzoylamino)-α-hydroxybenzenepropanoic Acid; [R-(R*,S*)]-β-(benzoylamino)-α-hydroxybenzenepropanoic Acid; (2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropionic Acid; (2R,3S)-N-Benzoyl-3-phenylisoserine; Paclitaxel Side Chain Impurity 1
Impurity:Paclitaxel Side Chain Impurity 1
CAS Number:132201-33-3
Molecular Formula:C₁₆H₁₅NO₄
Appearance:White to Off-White Solid
Melting Point:167-169°C
Molecular Weight:285.3
Storage:4°C
Solubility:Acetonitrile (Slightly), DMSO (Slightly), Ethanol (Slightly)
Category:Building Blocks; Amino Acids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(2R,3S)-N-Benzoyl-3-phenylisoserine is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites. (2R,3S)-N-Benzoyl-3-phenylisoserine shows cytotoxic, antiviral and immunomodulatory activity. Paclitaxel Side Chain Impurity 1.
References:Paal, K. et al.: Bioorg. Med. Chem., 15, 1323 (2007); Krawczyk, E. et al.: J. Pharm. Pharmacol., 57, 791 (2005);
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