Catalogue Number:B286275
Chemical Name:N-(N-Benzyloxycarbonyloxy)succinimide
Synonyms:1-[[(Benzyloxy)carbonyl]oxy]-2,5-pyrrolidinedione; 1-[[(Phenylmethoxy)carbonyl]oxy]-2,5-pyrrolidinedione; 1-[[[(Phenylmethyl)oxy]carbonyl]oxy]-2,5-pyrrolidinedione; Benzyl 2,5-dioxopyrrolid-1-yl Carbonate; Benzyl 2,5-dioxopyrrolidin-1-yl Carbonate; Benzyl N-succinimidyl Carbonate; Benzyl Succinimidyl Carbonate; Benzyloxycarbonyloxysuccinimide; Cbz-OSu; N-(Benzyloxycarbonyloxy)succinimide
CAS Number:13139-17-8
Molecular Formula:C₁₂H₁₁NO₅
Appearance:White Solid
Melting Point:80-81°C
Molecular Weight:249.22
Storage:4°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-(N-Benzyloxycarbonyloxy)succinimide is a reagent used in the preparation of peptide thioacids view peptide precursors. Also used in the preparation of aminoglycoside derivatives for the function of topoisomerase, both human and bacterial inhibition.
References:Pira, S. et al.: Org. Lett., 15, 5346 (2013); Fenner, A. et al.: Tetrahedron, 54, 3298 (2013);
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