Catalogue Number:B377010
Chemical Name:BIBX 1382 Dihydrochloride
Synonyms:N8-(3-Chloro-4-fluorophenyl)-N2-(1-methyl-4-piperidinyl)-pyrimido[5,4-d]pyrimidine-2,8-diamine Dihydrochloride
CAS Number:1216920-18-1
Alternate CAS #
Free Base: 196612-93-8
Molecular Formula:C₁₈H₁₉ClFN₇ • 2(HCl)
Appearance:Pale Yellow to Yellow Solid
Melting Point:>217°C (dec.)
Molecular Weight:387.84 + 2(36.46)
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors;
Applications:BIBX 1382 Dihydrochloride, is a potent, selective inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC50 = 3 nM).
References:Dittrich, et al.: Eur.J.Cancer 38, 1072, (2002);
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