Catalogue Number:B279973
Chemical Name:1-Benzylindole-5-boronic Acid Pinacol Ester
Synonyms:1-(Phenylmethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
CAS Number:1206163-56-5
Molecular Formula:C₂₁H₂₄BNO₂
Appearance:Pale Red Solid
Melting Point:128-131°C
Molecular Weight:333.23
Storage:-20°C
Solubility:Chloroform (Slightly), DMSO (Slightly)
Category:Building Blocks;
Applications:1-Benzylindole-5-boronic Acid Pinacol Ester acts as a reagent in the synthesis of 3,3-difluoro-2-oxindoles via electrophilic fluorination of indoles using N-fluorobenzenesulfonimide. Preparation of triazolopyridine compounds as JAK kinase inhibitors useful in the treatment of neurodegenerative and inflammatory diseases.
References:: Lim, Y., et al.: Org. Lett., 14, 5676; Menet, C., et al.: PCT Int. Appl. (2010), WO 2010010190 A1 20100128.
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