Catalogue Number:B230000
Chemical Name:9-(Benzylamino)-1,2,3,4-tetrahydroacridin-1-ol Maleate
Synonyms:1,2,3,4-Tetrahydro-9-[(phenylmethyl)amino]-1-acridinol (2Z)-2-Butenedioate; Suronacrine Hydrogen Maleate; Suronacrine Maleate;
CAS Number:113108-86-4
Molecular Formula:C₂₀H₂₀N₂O • C ₄H₄O₄
Appearance:White to Off-White Solid
Melting Point:142-144°C
Molecular Weight:304.39 + 116.07
Storage:-20°C
Solubility:DMSO (Slightly), Ethanol, Methanol (Slightly)
Category:Standards; Neurochemicals;
Applications:A potential Alzheimer’s Disease therapeutic of low toxicity. Exhibits biochemical and pharmacological profile similar to THA except that it is far less toxic and without measurable liver toxicity in humans. Also showed potent in vitro inhibition of the uptake of radiolabeled noradrenaline and dopamine.
References:Shutske, G.M., et al.: J. Med. Chem., 32, 1805 (1989)
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