Catalogue Number:B224865
Chemical Name:Benzyl 3-Aminoazetidine-1-carboxylate
Synonyms:3-Amino-1-(benzyloxycarbonyl)azetidine; 3-Amino-1-azetidinecarboxylic Acid Phenylmethyl Ester
CAS Number:112257-20-2
Molecular Formula:C₁₁H₁₄N₂O₂
Appearance:Off-White Low Melting Solid
Molecular Weight:206.24
Storage:4°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Building Blocks; Miscellaneous;
Applications:Benzyl 3-Aminoazetidine-1-carboxylate is used as a reagent in the synthesis of pyridazine and pyridine derivatives as nicotinamide phosphoribosyltransferase (NAMPT) inhibitors. Benzyl 3-Aminoazetidine-1-carboxylate is also used as the starting material in the synthesis of nitrogen-containing heterocycles as inhibitors of the hedgehog pathway.
References:Hansen, T.M., et al.: PCT Int. Appl. WO 2013170115 A1 20131114. Nov 14, 2013; Dai, M., et al.: PCT Int. Appl. WO 2008110611 A1 20080918. Sep 18, 2008
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