Catalogue Number:B278830
Chemical Name:(R)-2-Benzyl-3-hydroxypropyl Acetate
Synonyms:(2R)-2-(phenylmethyl)-1,3-propanediol 1-Acetate; (R)-2-(Phenylmethyl)-1,3-propanediol Monoacetate;
CAS Number:110270-49-0
Molecular Formula:C₁₂H₁₆O₃
Appearance:Colourless Oil
Molecular Weight:208.25
Solubility:Chloroform, DCM, Ethyl Acetate, Methanol
Category:Building Blocks; Amino Acids; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(R)-2-Benzyl-3-hydroxypropyl Acetate is an intermediate in the synthesis of Retorphan (R278500), a powerful and selective inhibitors of neprilysin and are being developed as therapeutic agents. Retorphan behave as the prodrug of the enantiomers of Thiorphan (T369500).
References:Monteil, T., et al.: Synth. Commun., 31, 211 (2001);
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