Catalogue Number:B188892
Chemical Name:Benzeneethan-α,α,β,β-d4-ol
CAS Number:107473-33-6
Molecular Formula:C₈H₆D₄O
Molecular Weight:126.19
Category:Building Blocks; Isotopic Labeled Analogues;
Applications:Benzeneethan-α,α,β,β-d4-ol is an intermediate used in the synthesis of Phenelzine-d4 Sulfate (P595902), which is a labeled hydrazine derivative that is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) and also inhibits GABA-transaminase (GABA-T), markedly increasing brain GABA levels. It is an antidepressant and anxiolytic used in the treatment of major depressive disorder (MDD) as well as other neural disorders.
References:MacKenzie, E.M. et al.: Neurochem. Res., 33, 430 (2008);Chiche, F. et al.: Mol. Pharmacol., 75, 1052 (2009); McKenna, K.F, et al.: J. Neural Trans., 41, 115 (1994);
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