Catalogue Number:D288723
Chemical Name:7-Deacetilgedunin
Synonyms:7-Deacetoxy-7-hydroxygedunin; 7-Deacetoxy-7α-hydroxygedunin; 7-Deacetoxy-7α-hydroxyoxygedunin; 7-Deacetylgedunin; Deacetylgedunin; (1S,3aS,4aR,4bS,5R,6aR,10aR,10bR,12aS)-1-(3-Furanyl)-1,5,6,6a,7,10a,10b,11,12,12a-decahydro-5-hydroxy-4b,7,7,10a,12a-pentamethyloxireno[c]phenanthro[1,2-d]pyran-3,8(3aH,4bH)-dione
CAS Number:10314-90-6
Molecular Formula:C₂₆H₃₂O₆
Molecular Weight:440.53
Category:Standards; Natural Products;
Applications:7-Deacetilgedunin is a dervative of Gedunin (G303503), a naturally occurring Hsp90 inhibitor. In vitro, Gedunin induces Hsp90-dependent client protein degradation and displays antiproliferative activity. Also an extract from neem seeds and may be responsible for its antibacterial activity.
References:Gao, Q. et al.: Natural. Prod. Res., 31, 1739 (2017); Lee, S. et al.: Phytomed. Int. J. Phytother. Phytopharm., 15, 533 (2008);
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