Catalogue Number:B207930
Chemical Name:N4-Benzoyl-2’-deoxy-5’-O-DMT-cytidine 3’-CE Phosphoramidite
Synonyms:N-Benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-cytidine 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; N4-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine-3′-O-[O-(2-cyanoethyl)-N,N’-diisopropylphosphoramidite]; DMT-dC(bz) Phosphoramidite
CAS Number:102212-98-6
Molecular Formula:C₄₆H₅₂N₅O₈P
Appearance:Off-White Solid
Melting Point:>84°C (dec.)
Molecular Weight:833.91
Storage:4°C, Inert atmosphere
Solubility:Chloroform, DMSO, Methanol (Slightly)
Category:Building Blocks; Chiral Molecules; Miscellaneous;
Applications:N4-Benzoyl-2’-deoxy-5’-O-DMT-cytidine 3’-CE Phosphoramidite is used to prepare antisense oligonucleotides containing conformationally constrained methoxyaminomethylene and aminooxymethylene and aminomethylene bridged nucleoside analogs.
References:Prakash, T., et al.: J. Med. Chem., 53, 1636 (2010); Winkler, J., et al.: Eur. J. Med. Chem., 44, 670 (2009)
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