CAS:100574-22-9|5,​5-​Dioxide Thioridazine Disulfoxide

Catalogue Number:D100575
Chemical Name:5,​5-​Dioxide Thioridazine Disulfoxide
Synonyms:10-(2-(1-Methylpiperidin-2-yl)ethyl)-2-(methylsulfonyl)-10H-phenothiazine 5,5-dioxide
CAS Number:100574-22-9
Molecular Formula:C₂₁H₂₆N₂O₄S₂
Appearance:Light Yellow to Yellow Solid
Melting Point:>70°C (dec.)
Molecular Weight:434.57
Storage:-20°C, Hygroscopic
Solubility:Dichloromethane (Slightly), Mthanol (Slightly)
Category:Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5,​5-​Dioxide Thioridazine Disulfoxide is the impurity of Thioridazine Hydrochloride (T368800). Thioridazine HCl is a dopamine receptor blocker and antipsychotic. It is the parent compound of sulforidazine and mesoridazine. _x000b_This compound has been reported to bind strongly to dopamine receptors on cancer stem cells and cause differentiation leaving normal cells alone.
References:Goldenthal, E.I., Toxicol. Appl. Pharmacol., 18, 185 (1971), Abdel-Moety, E.M., et al.: Anal. Profile Drug Subs., 18, 459 (1989),
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