Ampicillin Desoxocarboxylic Acid-[(R)-(Phenyl-d5)glycine]

Chemical Name:Ampicillin Desoxocarboxylic Acid-[(R)-(Phenyl-d5)glycine]
Synonyms:(αR)-α-[[[(2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-yl]carbonyl]amino]benzeneacetic Acid-d5
Molecular Formula:C₂₄H₂₁D₅N₄O₅S
Molecular Weight:487.58
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;
Applications:Ampicillin Desoxocarboxylic Acid-[(R)-(Phenyl-d5)glycine] is deuterium labeled Ampicillin Desoxocarboxylic Acid-[(R)-Phenylglycine] (A634355). Ampicillin Desoxocarboxylic Acid-[(R)-Phenylglycine] can be used to develop HPLC methods that detect compounds or impurities related to ampicillin in bulk drug. Ampicillin Desoxocarboxylic Acid-[(R)-Phenylglycine] is a related compound of Ampicillin (A634300), a β-lactam antibiotic used for treating bacterial infection. Ampicillin interferes with cell wall synthesis in bacteria.
References:Raju, Ch. B. V. N., et al.: Anal Chem : Ind J, 7, 354 (2008); Fisher, J. F., et al.: Chem. Rev. 105, 395 (2005); Sill, M. L., et al.: Antimicrob. Agents Chemother. 52, 1551 (2008); Ivashkiv, E., et al.: Anal. Profiles Drug Subs. 2, 1 (1973)
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