Chemical Name:Aliskiren-d6 N-Maleic Acid (Mixture of Diastereomers)
Synonyms:2-(((3S,5S,6S,8S)-8-((3-Amino-2,2-dimethyl-3-oxopropyl)carbamoyl)-6-hydroxy-3-(4-methoxy-3-(3-methoxypropoxy)benzyl)-2,9-dimethyldecan-5-yl)amino)succinic Acid-d6
Molecular Formula:C₃₄H₅₁D₆N₃O₁₀
Molecular Weight:673.87
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Aliskiren-d6 N-Maleic Acid (Mixture of Diastereomers) is the labeled analogue of Aliskiren N-Maleic Acid (Mixture of Diastereomers) (A536005), a degradation impurity of Aliskiren Hemifumarate (A536001), an orally active, synthetic nonpeptide renin inhibitor. Antihypertensive.
References:Lefevre, G., et al.: J. Immunoassay, 21, 65 (2000); Allikments, K., et al.: Curr. Opin. Invest. Drugs, 3, 1479 (2002); Wood, J.M., et al.: Biochem. Biophys. Res. Commun., 308, 698 (2003); Grandman, A.H., et al.: Circulation, 111, 1012 (2005)
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