Chemical Name:Afatinib Dimer
Synonyms:(E)-N-(4-((3-Chloro-4-fluorophenyl)(4-((4-((3-chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-1-(dimethylamino)-4-oxobutan-2-yl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
Molecular Formula:C₄₈H₅₀Cl₂F₂N₁₀O₆
Molecular Weight:971.88
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Afatinib Dimer is a dimer of Afatinib (A355300); an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.
References:Schroeder, J., et al.: PCT Int. Appl. WO 2007085638 A1 20070802. Aug 2, 2007
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