Chemical Name:9-(2-Hydroxypropyl)adenine-13C5
Synonyms:6-Amino-α-methyl-9H-purine-9-ethanol-13C5; (RS)-9-(2-Hydroxypropyl)adenine-13C5; 9-(2-Hydroxyprop-1-yl)adenine-13C5; DL-9-(2-Hydroxypropyl)adenine13C5; DL-6-amino-α-methyl-9H-Purine-9-ethanol-13C5; (±)-6-amino-α-methyl-9H-Purine-9-ethanol-13C5;
Alternate CAS #:14047-26-8
Molecular Formula:C₃¹³C₅H₁₁N₅O
Molecular Weight:198.17
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:9-(2-Hydroxypropyl)adenine-13C5 is an intermediate used in the synthesis of rac Tenofovir-13C5 (>90%) (T018501), which is he isotope labelled analog of Tenofovir (T018500); an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. Also used as an anti-HIV agent and antiviral.
References:Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005); Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006); Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)
To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low temperature products will be delivered with ice bags. As for the products stored at room temperature, they will not be packed with ice bags or dried ice. Taskcm is committed to providing cost-effective products that facilitate drug delivery with our customers.
