Chemical Name:6-Hydroxy Alosetron
Synonyms:2,3,4,5-Tetrahydro-6-hydroxy-5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H-pyrido[4,3-b]indol-1-one; 2,3,4,5-Tetrahydro-6-hydroxy-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one; 6-Hydroxy Lotronex; Alosetron 6-Hydroxy Impurity
Impurity
Alosetron 6-Hydroxy Impurity
CAS Number:128486-89-5
Molecular Formula:C₁₇H₁₈N₄O₂
Molecular Weight:310.35
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:6-Hydroxy Alosetron is a derivative of Alosetron (A575500), serotonin 5HT3-receptor antagonist. Used in treatment of irritable bowel syndrome.
References:Camilleri, M., et al.: Lancet, 355, 1035 (2000), Nestorov, I., et al.: Drug Metab. Dispos., 30, 276 (2002), Lewis, D., et al.: Drug Metab. Rev., 35, 1 (2003),
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