6α-Hydroxy Estrone

Chemical Name:6α-Hydroxy Estrone
Synonyms:(6α)-3,6-Dihydroxyestra-1,3,5(10)-trien-17-one; 3,6α-Dihydroxyestra-1,3,5(10)-trien-17-one; 6α-Hydroxyestrone;
CAS Number:1476-78-4
Molecular Formula:C₁₈H₂₂O₃
Molecular Weight:286.37
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;
Applications:The oxidative 6α-metabolite of 17β-Estradiol (E887995) and Estrone (E889050) formed by 15 selectively expressed human cytochrome p450 isoforms.
References:Grose, K., et al.: Chem. Res. Toxicol., 5, 188 (1992), Chang, Y., et al.: Biochem. Pharmacol., 58, 825 (1999), Hong, C., et al.: Carcinogenesis, 23, 1297 (2002),
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