Chemical Name:(5S)-3-(3-Fluorophenyl)-5-(hydroxymethyl)-2-pxazolidinone
CAS Number:919081-42-8
Molecular Formula:C₁₀H₁₀FNO₃
Molecular Weight:211.19
Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
Applications:(5S)-3-(3-Fluorophenyl)-5-(hydroxymethyl)-2-pxazolidinone is an impurity of the drug (S)-Tedizolid (T013765), which is an antibiotic used to treat skin related bacterial infections. In addition, (5S)-3-(3-Fluorophenyl)-5-(hydroxymethyl)-2-pxazolidinone can be used to develop HIV-1 protease inhibitors with picomolar affinities.
References:Michalska, K., et al.: J. Mol. Struct., 1115, 136 (2016); Ali, A., et al.: J. Med. Chem. 49, 7342 (2006)
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