Chemical Name:5-(Methoxycarbonylmethyl)-2-thiouridine
Synonyms:3,5-Dinitro-benzyl alcohol; 3,5-Dinitrobenzyl alcohol; 3,5-Dinitrobenzenemethanol; 1,2,3,4-Tetrahydro-4-oxo-1-β-D-ribofuranosyl-2-thioxo-methyl Ester 5-Pyrimidineacetic Acid
CAS Number:20299-15-4
Molecular Formula:C₁₂H₁₆N₂O₇S
Molecular Weight:332.33
Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5-(Methoxycarbonylmethyl)-2-thiouridine can be used as analyte in biological study for attomole quantification and global profile of RNA modifications in study of epitranscriptome of human neural stem cells. It can also be used to biological computational studies to provide insights into effects of modified ribonucleotides and Mg2+ on structures and stabilities of tRNAs. A trace nucleoside, isolated from yeast transfer RNA. A nucleoside in the anticodon at the wobble position of some Saccharomyces cerevisiae bacteria.
References:Basanta-Sanchez, M., et al.: Nucleic Acids Res., 44, 26 (2016); Xu, Y., et al.: Bioorgan. Med. Chem., 24, 4826-4834 (2016);
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