Chemical Name:5-Bromo-2-chlorothien-3-yl Tioconazole Hydrochloride
Synonyms:5-Bromo-2-chloro-3-thenyl)-oxy]-phenethyl]imidazole Hydrochloride; USP Tioconazole Related Compound C;
Molecular Formula:C₁₆H₁₃BrCl₄N₂OS
Molecular Weight:503.07
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5-Bromo-2-chlorothien-3-yl Tioconazole Hydrochloride is an impurity in the synthesis of Tioconazole (T444680), an antifungal that is more active than Fluconazole (F421000) or Voriconazole (V760000) against Candida glabrata mutant strains. Antifungal (topical).
References:Jevons, S., et al.: Antimicrob. Agents Chemother., 15, 597 (1979), Clayton, Y.M., et al.: Clin. Exp. Dermatol., 7, 543 (1982), Marriott, M.S., et al.: Dermatologica, 166, 1 (1983),
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