4-Hydroxy-3,4-dihydro-gemcitabine

Chemical Name:4-Hydroxy-3,4-dihydro-gemcitabine
Synonyms:6-amino-3-(3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one
Molecular Formula:C₉H₁₃F₂N₃O₅
Molecular Weight:281.21
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-Hydroxy-3,4-dihydro-gemcitabine is an impurity of Gemcitabine (G305028), which is used for breast cancer treatment. First-line treatment for locally advanced pancreatic cancer.
References:Hamsici, S., et al.: Bioconjugate Chem., (2017); Peng, T., et al.: J. Cell. Biochem., (2017)
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