(3aR-cis)-Hexahydro-4-(phenylmethyl)-2H-furo[3,2-b]pyrrol-2-one-d2

Chemical Name:(3aR-cis)-Hexahydro-4-(phenylmethyl)-2H-furo[3,2-b]pyrrol-2-one-d2
Alternate CAS #:unlabelled: 121686-91-7
Molecular Formula:C₁₃H₁₃D₂NO₂
Molecular Weight:219.28
Category:Standards; Chiral Molecules; Isotopic Labeled Analogues; Environmental Standards, Mutagens and Metabolites;
Applications:(3aR-cis)-Hexahydro-4-(phenylmethyl)-2H-furo[3,2-b]pyrrol-2-one-d2is synthesized from pyroglutamic acid. Also, it is an intermediate used in the synthesis of Monocrotaline-d4 (M526002), which is labelled Monocrotaline (M526000) which is a toxic pyrrolizidine alkaloid isolated from Crotalaria spp. It is used for inducing pulmonary diseases in rats.
References:Ikota, N., et al.: Heterocycles, 27, 2535-2527 (1988); Newberne, P.M., et al.: Toxicol. Appl. Pharmacol., 18, 387 (1971), Bober, M.A., et al.: Toxicon, 27, 1059 (1989), Wilson, D.W., et al.: Crit. Rev. Toxicol., 22, 307 (1992)
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