3,6-Dichloro-2-pyrazinecarbonitrile-13C3

Chemical Name:3,6-Dichloro-2-pyrazinecarbonitrile-13C3
Alternate CAS #:356783-16-9
Molecular Formula:C₂¹³C₃HCl₂N₃
Molecular Weight:176.96
Category:Building Blocks; Isotopic Labeled Analogues; Miscellaneous;
Applications:3,6-Dichloro-2-pyrazinecarbonitril-13C3 is an intermediate in the synthesis of Favipiravir-13C3 (F103352), which is the isotope labelled analog of Favipiravir. Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever. It is a COVID19-related research product.
References:Oestereich, L., et al.: Antiviral Res., 105, 17 (2014); Baranovich, T., et al.: J. Virol. 87, 3741 (2013)
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