Chemical Name:3-cis-Hydroxyglipizide
Synonyms:Hydroxycyclohexyl]amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl-2-pyrazinecarboxamide; 1-[4-[2-(5-Methylpyrazine-2-carboxamido)ethyl]phenylsulfonyl]-3-(3-cis-hydroxycyclohexyl)urea; N-[4-[β-(5-Methylpyrazine-2-carboxamido)ethyl]benzenesulfonyl]-N’-(3-cis-hydroxycyclohexyl)urea;
CAS Number:38207-37-3
Molecular Formula:C₂₁H₂₇N₅O₅S
Molecular Weight:461.53
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3-cis-Hydroxyglipizide is a metabolite of Glipizide (G410225), a sulfonylurea hypoglycemic agent. Used as an antidiabetic.
References:Ambrogi, et al.: Arzneimittel-Forsch., 21, 200 (1971), Fuccella, et al.: J. Clin. Pharmacol., 13, 68 (1973), Brogden, R.N., et al.: Drugs, 18, 329 (1979), Lebovitz, H.E., et al.: Pharmacother., 5, 63 (1985)
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