3-[(6-Chlorothiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide

Chemical Name:3-[(6-Chlorothiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide
Synonyms:3-[(6-Chlorothiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide; PC 190723
CAS Number:951120-33-5
Molecular Formula:C₁₄H₈ClF₂N₃O₂S
Molecular Weight:355.75
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3-[(6-Chlorothiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide is a small molecule cell-cycle inhibitor and has been used as an antibacterial agent. 3-[(6-Chlorothiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide was found to inhibit bacterial cell division protein FtsZ.
References:Elsen, N.L., et al.: J. Am. Chem. Soc., 134, 12342 (2012); Sorto, N.A., et al.: J. Org. Chem., 75, 7946 (2010); Andreu, J.M., et al.: J. Biol. Chem., 285, 14239 (2010);
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