(2S,4S,4’R)-2′,2′-Dimethyl[4,4′-bi-1,3-dioxolane]-2-methanol

Chemical Name:(2S,4S,4’R)-2′,2′-Dimethyl[4,4′-bi-1,3-dioxolane]-2-methanol
Synonyms:[2S-[2α,4α(S*)]]-2′,2′-Dimethyl-[4,4′-bi-1,3-dioxolane]-2-methanol;
CAS Number:145354-78-5
Molecular Formula:C₉H₁₆O₅
Molecular Weight:204.22
Applications:(2S,4S,4’R)-2′,2′-Dimethyl[4,4′-bi-1,3-dioxolane]-2-methanol is an intermediate used in the synthesis of Troxacitabine (T805580), which is a nucleoside analogue with potential anticancer activity. Troxacitabine have been studied in patients with refractory lymphoproliferative diseases.
References:Robak, T., et al.: Curr. Med. Chem., 18, 638 (2011); Kornblau, S.M., et al.: Clin. Cancer. Res., 16, 3721 (2010);
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