Chemical Name:25-Hydroxy-cholesterol 3-Sulfate Ester Sodium Salt-d6
Synonyms:Sodium (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl Sulfate-d6
Alternate CAS #:Unlabelled: 1174047-40-5
Molecular Formula:C₂₇H₃₉D₆NaO₅S
Molecular Weight:510.73
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;
Applications:25-Hydroxy-cholesterol 3-Sulfate Ester Sodium Salt-d6 is the isotope labelled analog of 25-Hydroxy-cholesterol 3-Sulfate Ester Sodium Salt (H825760). 25-Hydroxy-cholesterol 3-Sulfate Ester is a derivative of 4β-Hydroxy Cholesterol (H917980), a metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.
References:Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995),
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