Chemical Name:21-Hydroxy-16Alpha-methylpregna-1,4,9(11)-triene-3,20-dione
Synonyms:(16α)-21-Hydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione; Dexamethasone Impurity;
CAS Number:56016-90-1
Molecular Formula:C₂₂H₂₈O₃
Molecular Weight:340.46
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:21-Hydroxy-16α-methylpregna-1,4,9(11)-triene-3,20-dione is the impurity of Dexamethasone (D298800), which is a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation; it inhibits the induction of nitric oxide synthase.
References:Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995); Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999); Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999);
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