Chemical Name:(1’R,2R,3S)-Defluoro Fosaprepitant Dimeglumine
Molecular Formula:C₃₇H₅₇F₆N₆O₁₆P
Molecular Weight:986.84
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(1’R,2R,3S)-Defluro Fosaprepitant Dimeglumine, is an impurity of Fosaprepitant (F727300) isomer, which is a selective neurokinin-1 (NK-1) receptor antahonist. Fosaprepitant is an antiemetic drug, a Aprepitant (A729800) prodrug.
References:Tattersall, F., et al.: Neuropharmacol., 39, 652 (2000), Cocquyt, V., et al.: Eur. J. Canc., 37, 835 (2001), Lasseter, K., et al.: J. Clin. Pharmacol., 47, 834 (2007), Marbury, T., et al.: Anesthes., Analges., 109, 418 (2009),
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