Chemical Name:1,4-Bis(trifluoromethyl)benzene-13C6
CAS Number:286013-13-6
Alternate CAS #:433-19-2
Molecular Formula:C₂¹³C₆H₄F₆
Molecular Weight:220.06
Category:Building Blocks; Isotopic Labeled Analogues; Miscellaneous;
Applications:1,4-Bis(trifluoromethyl)benzene-13C6 is an intermediate in the synthesis of Dutasteride-13C6 (D735002), which is a labeled Dutasteride (D735000). Dutasteride is a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.
References:Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),
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