Chemical Name:1,3-Bis(tertButyldimethylsilyl)-25-Tetrahydropyranyl Paricalcitol
Molecular Formula:C₄₄H₈₀O₄Si₂
Molecular Weight:729.27
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(((1R,3R)-5-((E)-2-(1-((E)-5,6-Dimethyl-6-((tetrahydro-2H-pyran-2-yl)oxy)hept-3-en-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)cyclohexane-1,3-diyl)bis(oxy))bis(tert-butyldimethylsilane) is an intermediate in the synthesis of 24R-Paricalcitol (P195365), which is a useful intermediate that is structurally related to Paricalcitol (P195300), a synthetic analog of Vitamin D that is classified an an antihyperparathyroid.
References:Sidek, H., et al.: Biochim. Biophys. Acta, 801, 26 (1984), Ciftci, M., et al.: J. Pharmacol., 54, 275 (2002)
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