Chemical Name:11-epi Lubiprostone
Molecular Formula:C₂₀H₃₂F₂O₅
Molecular Weight:390.46
Category:Building Blocks; Miscellaneous;
Applications:11-epi Lubiprostone is an analog of Lubiprotone (L473500). Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation.
References:Farthing, M., et al.: Drugs, 56, 11 (1998), Pare, P., et al.: Am. J. Gastroenterol., 96, 3130 (2001); Sloots, C., et al.: Aliment. Pharmacol. Ther., 16, 759 (2002), Coremans, G., et al.: Digestion, 67, 82 (2003);
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