(βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1-Methylethyl Ester

Chemical Name:(βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1-Methylethyl Ester
Synonyms:Atorvastatin Isopropyl Ester
CAS Number:1035205-25-4
Alternate CAS #:134523-00-5
Molecular Formula:C₃₆H₄₁FN₂O₅
Molecular Weight:600.72
Category:Standards; Chiral Molecules; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1-Methylethyl Ester, is an impurity of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
References:Shaw, M.K et al., Biochem. Biophys. Res. Commun. 170(2), 726-734 (1990)
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