CAS:205654-80-4|(2R,4S)-Benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate
Catalogue Number:B287516Chemical Name:(2R,4S)-Benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylateSynonyms:Benzyl (2R,4S)-5-Oxo-2,4-diphenyl-1,3-oxazolidine-3-carboxylate; Intermediate of RolapitantCAS Number:205654-80-4Molecular Formula:C₂₃H₁₉NO₄Molecular Weight:373.4Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(2R,4S)-Benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate is an intermediate in the preparation of Rolapitant (R639800). Rolapitant is an NK1 receptor antagonist that is used in the treatment of chemotherapy-induced nausea and vomiting.References:Rojas, C. et al.: Cancer Treat. Rev., 41, 904 (2015); Navari, R. et al.: Exp. […]