Drug Delivery

Chemical Name:Di-O-cysteinyl-glycinoyl Curcumin-d6Synonyms:4-((1E,6E)-7-(4-(2-((R)-2-Amino-3-mercaptopropanamido)acetoxy)-3-methoxyphenyl)-3,5-dioxohepta-1,6-dien-1-yl)-2-methoxyphenyl 2-((S)-2-amino-3-mercaptopropanamido)acetate-d6; 2,2′-[[(1E,6E)-3,5-dioxo-1,6-heptadiene-1,7-diyl]bis(2-methoxy-4,1-phenylene)] Ester L-cysteinyl-glycine-d6;Alternate CAS #:1042019-87-3 unlabelledMolecular Formula:C₃₁H₃₀D₆N₄O₁₀S₂Molecular Weight:694.81Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Di-O-cysteinyl-glycinoyl Curcumin-d6 is the isotope labelled analog of Di-O-cysteinyl-glycinoyl Curcumin. Di-O-cysteinyl-glycinoyl curcumin is a metabolite of curcumin (C838500), which is a natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and antioxidant properties. Induces apoptosis […]

Chemical Name:Dibenzylcyclooctyne-PEG4-ATTO-425Synonyms:ATTO425; DBCO-PEG4-ATTO-425Molecular Formula:C₅₁H₆₂N₄O₁₁Molecular Weight:907.06Category:Research Tools; Molecular Biology; Fluorescent Reagents;Applications:Dibenzylcyclooctyne-PEG4-ATTO-425, is a Fluorescent dye. (Abs/Em = 436/484 nm)References:Liu et al. J Bacteriol 198:3045. (2016);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to […]

Chemical Name:(10β, 8β)-Dihydroxy NaltrexoneSynonyms:(4R,4aS,5S,7aR,12bS,13R)-3-(Cyclopropylmethyl)-4a,5,9,13-tetrahydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-oneMolecular Formula:C₂₀H₂₃NO₆Molecular Weight:373.4Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(10β, 8β)-Dihydroxy Naltrexone is a derivative of Naltrexone (N285750), a nonselective opioid receptor antagonist; congener of Naloxone.References:Maickel, R.P., et al.: Ann. N.Y. Acad. Sci., 281, 321 (1976), Gritz, E.R., et al.: Clin. Pharmacol. Ther. 19, 773 (1976), Gonzales, J.P., et al.: Drugs, 35, 192 (1988), Berg, B.J., […]

Chemical Name:(2S,2’S)-3,3′-(((6,6′-Dihydroxy-5,5′-diiodo-[1,1′-biphenyl]-3,3′-diyl)bis(oxy))bis(3,5-diiodo-4,1-phenylene))bis(2-aminopropanoic acid)CAS Number:2088032-54-4Alternate CAS #:Parent compound: 51-48-9Molecular Formula:C₃₀H₂₂I₆N₂O₈Molecular Weight:1299.93Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(2S,2’S)-3,3′-(((6,6′-Dihydroxy-5,5′-diiodo-[1,1′-biphenyl]-3,3′-diyl)bis(oxy))bis(3,5-diiodo-4,1-phenylene))bis(2-aminopropanoic acid) is a Levothyroxine impurity of Thyroxine (T425600), which is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Thyroxine is deiodinated in peripheral tissues to the active metabolite, liothyronine, which has been used to treat hyperlipidemia.References:Post, A., et […]

Chemical Name:(αR)-5,6-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamineCAS Number:802918-36-1Molecular Formula:C₂₂H₂₄F₃NMolecular Weight:359.43Category:Building Blocks;Applications:(αR)-5,6-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine is synthetically prepared though a double bond migration in Heck reaction during the preparation of cinacalcet congeners. This enantiomerically pure material is seperated from its counter part, (αR)-7,8-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine (D455330) using HPLC.References:Wang, X., et al.: Tetrahedron Lett., 45, 8355 (2004)To ensure the stability of our products, the efficient express delivery […]

Chemical Name:(αR)-7,8-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamineCAS Number:802918-35-0Alternate CAS #:HCl: 1020414-33-8Molecular Formula:C₂₂H₂₄F₃NMolecular Weight:359.43Category:Building Blocks;Applications:(αR)-7,8-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine is synthetically prepared though a double bond migration in Heck reaction during the preparation of cinacalcet congeners. This enantiomerically pure material is seperated from its counter part, (αR)-5,6-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine (D455335) using HPLC.References:Wang, X., et al.: Tetrahedron Lett., 45, 8355 (2004)To ensure the stability of our products, the […]

Chemical Name:24,25-Dihydroxy Vitamin D2 3-HemisuccinateMolecular Formula:C₃₂H₄₈O₆Molecular Weight:528.72Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:24,25-Dihydroxy Vitamin D2 3-hemisuccinate is a derivative of Vitamin D2 (V676040), which is naturally synthesized by plants and used in the fortification of foods.References:Horst, R., et al.: Biochemistry, 29, 578 (1990); Kanis, J.: J. Bone Joint Surg. Br., 64, 542 (1982)To ensure the stability of our […]

Chemical Name:(4R)-5-(3′,4′-Dihydroxyphenyl)-γ-valerolactone-d3 ((-)-Epicatechin Metabolite)Synonyms:(5R)-5-[(3,4-Dihydroxyphenyl)methyl]dihydro-2(3H)furanone-d3;Alternate CAS #:Unlabelled: 191666-22-5Molecular Formula:C₁₁H₉D₃O₄Molecular Weight:211.23Category:Standards; Isotopic Labeled Analogues;Applications:A labelled metabolite of (-)-Epicatechin (E582260).References:Li, C. et al.: Chem. Res. Tox., 14, 702 (2001);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of […]

Chemical Name:7,8-Dihydroxy-6-methoxycoumarin 5-beta-D-GlucosideSynonyms:7,8-Dihydroxy-6-methoxy-5-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-oneMolecular Formula:C₁₆H₁₈O₁₁Molecular Weight:386.31Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;Applications:7,8-Dihydroxy-6-methoxycoumarin 5-β-D-Glucoside is an isomer of 5-Hydroxyfraxetin 8-β-D-Glucoside (H942540); a derivative of Fraxetin (F763960) which is a coumarin compound with anti-oxidant and anti-inflammatory activity. It also acts as a protective agent against hyperuricemia and renal dysfunction.References:Witaicenis, A. et al.: Phytomed. 21, 240 (2014); Chen, X. […]

Chemical Name:(2S,2’S)-3,3′-(((6,6′-Dihydroxy-5-iodo-[1,1′-biphenyl]-3,3′-diyl)bis(oxy))bis(3,5-diiodo-4,1-phenylene))bis(2-aminopropanoic Acid)CAS Number:2088032-60-2Alternate CAS #:Parent compound: 51-48-9Molecular Formula:C₃₀H₂₃I₅N₂O₈Molecular Weight:1174.03Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(2S,2’S)-3,3′-(((6,6′-Dihydroxy-5-iodo-[1,1′-biphenyl]-3,3′-diyl)bis(oxy))bis(3,5-diiodo-4,1-phenylene))bis(2-aminopropanoic Acid) is a Levothyroxine impurity of Thyroxine (T425600), which is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Thyroxine is deiodinated in peripheral tissues to the active metabolite, liothyronine, which has been used to treat hyperlipidemia.References:Post, A., et […]