Drug Delivery

Chemical Name:S-(-)-DIOA-D9Synonyms:(S)-2-((2-(butyl-d9)-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy)acetic acidMolecular Formula:C₂₀H₁₅D₉Cl₂O₄Molecular Weight:408.4Category:Building Blocks; Isotopic Labeled Analogues; Miscellaneous;To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried […]

Chemical Name:S-(-)-DIOASynonyms:(S)-2-((2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy)acetic acidCAS Number:81166-48-5Molecular Formula:C₂₀H₂₄Cl₂O₄Molecular Weight:399.3Category:Research Tools; Molecular Biology; Pharmaceutical/API Drug Impurities/Metabolites;Applications:S-(-)-DIOA can be useful in the study of agents for the treatment of brain injury.References:Cragoe, E. J., Jr., et al.: J. Med. Chem., 25, 567 (1982)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that […]

Chemical Name:R-(+)-DIOA-D9Synonyms:(R)-2-((2-(butyl-d9)-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy)acetic acidMolecular Formula:C₂₀H₁₅D₉Cl₂O₄Molecular Weight:408.4Category:Building Blocks; Isotopic Labeled Analogues; Miscellaneous;To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried […]

Chemical Name:cis-5-cis-13-Docosadienoic AcidSynonyms:5,13-Docosadienoic acid, (Z,Z); (5Z,13Z)-5,13-Docosadienoic acidCAS Number:676-39-1Molecular Formula:C₂₂H₄₀O₂Molecular Weight:336.56Category:Research Tools; Molecular Biology;Applications:cis-5-cis-13-Docosadienoic Acid can be useful in the study of surface bacterial community, fatty acid profile, and antifouling activity of two sponges.References:Lee, O. O., et al.: Mar. Ecol.: Prog. Ser., 339, 25 (2007)To ensure the stability of our products, the efficient express delivery service […]

Chemical Name:Tamoxifen 4-N,N-Dimethyl-2-[4-(phenylmethyl)phenoxy]ethanamineSynonyms:(E)-2-(4-(1-(4-((4-(2-(Dimethylamino)ethoxy)phenyl)(phenyl)methyl)phenyl)-2-phenylbut-1-en-1-yl)phenoxy)-N,N-dimethylethanamine; 2-(4-(1-(4-((4-(2-(Dimethylamino)ethoxy)phenyl)(phenyl)methyl)phenyl)-2-phenylbut-1-en-1-yl)phenoxy) TamoxifenCAS Number:2125703-03-7Molecular Formula:C₄₃H₄₈N₂O₂Molecular Weight:624.85Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:2-(4-(1-(4-((4-(2-(dimethylamino)ethoxy)phenyl)(phenyl)methyl)phenyl)-2-phenylbut-1-en-1-yl)phenoxy) Tamoxifen is an impurity of Tamoxifen whcih is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4.References:Sutherland, R., et […]

Chemical Name:De((S)-1-((S)-2-(3,4,5-Trimethoxyphenyl)butanoyl)piperidine-2-carboxylic Acid) dTAG-7Synonyms:2-(2-((R)-3-(3,4-Dimethoxyphenyl)-1-hydroxypropyl)phenoxy)-N-(1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-2-oxo-7,10,13-trioxa-3-azahexadecan-16-yl)acetamide;Molecular Formula:C₄₄H₅₄N₄O₁₄Molecular Weight:862.92Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:De((S)-1-((S)-2-(3,4,5-Trimethoxyphenyl)butanoyl)piperidine-2-carboxylic Acid) dTAG-7 is an intermediate for the synthesis of dTAG-7 (D710015), which is a degradation tag, was tested for its efficiency at depleting FKBP12F36V -MELK(sg3R) and was found to have significantly degraded FKBP12F36V -MELK(sg3R) within 4 hours.Used in the study of cancer […]

Chemical Name:((DOTA-HYNIC)-D-alanyl)-L-proline-boronic AcidSynonyms:2,2′,2”-(10-(2-(2-(5-(((R)-1-((R)-2-Boronopyrrolidin-1-yl)-1-oxopropan-2-yl)carbamoyl)pyridin-2-yl)hydrazinyl)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic AcidMolecular Formula:C₂₉H₄₆BN₉O₁₁Molecular Weight:707.54Category:Standards; Chiral Molecules; Miscellaneous;Applications:((DOTA-HYNIC)-D-alanyl)-L-proline-boronic Acid is a compound useful in organic synthesis.To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low […]

Chemical Name:3,4-DivanilyltetrahydrofuranSynonyms:4,4′-[(Tetrahydro-3,4-furandiyl)bis(methylene)]bis[2-methoxyphenol]; 3,4-Divanillyltetrahydrofuran;CAS Number:34730-78-4Molecular Formula:C₂₀H₂₄O₅Molecular Weight:344.4Category:Standards; Pheromones; Steroids;Applications:3,​4-​Divanilyltetrahydrofuran is the main active ingredient of nettle root which can increase steroid hormones in the bloodstream for many of bodybuilders. 3,4-Divanilyltetrahydrofuran is used in preparations for enhancing libido in mammals.References:Shan, C., et al.: J. Chromatogr. B., 1008, 250 (2016); Farber, M., et al.: From U.S. Pat. Appl. […]

Chemical Name:4-epi-DolutegravirSynonyms:(4S,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamideCAS Number:1357289-37-2Molecular Formula:C₂₀H₁₉F₂N₃O₅Molecular Weight:419.38Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:4-epi-Dolutegravir, is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor.References:Kobayashi, M. et al. Antimicrob Agents Chemother., 55, 813 (2011); Garrido, C. et al.: Antiviral, Res., 90, 164 (2011); Lenz, J.C.C. et al.: Exp. Opin. Invest. Drugs, 20, 537 (2011);To ensure the stability of […]

Chemical Name:Dolutegravir RR IsomerSynonyms:(4R,​12aR)​-N-​[(2,​4-Difluorophenyl)​methyl]​-​3,​4,​6,​8,​12,​12a-​hexahydro-​7-​hydroxy-​4-​methyl-​6,​8-​dioxo-​2H-pPyrido[1′,​2′:4,​5]​pyrazino[2,​1-​b]​[1,​3]​oxazine-​9-​carboxamideCAS Number:1357289-29-2Molecular Formula:C₂₀H₁₉F₂N₃O₅Molecular Weight:419.38Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;Applications:Dolutegravir RR Isomer is an isomer of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in […]