CAS:1792999-26-8|cis-4-[[2-(1H-Benzimidazol-6-ylamino)-8-quinazolinyl]oxy]-cyclohexanol
Catalogue Number:B197005Chemical Name:cis-4-[[2-(1H-Benzimidazol-6-ylamino)-8-quinazolinyl]oxy]-cyclohexanolSynonyms:NCB-0846CAS Number:1792999-26-8Molecular Formula:C₂₁H₂₁N₅O₂Appearance:Off-White to Light Yellow SolidMolecular Weight:375.42Storage:-20°CSolubility:DMSO (Slightly), Methanol (Slightly)Category:Standards; Enzyme Activators and Inhibitors;Applications:cis-4-[[2-(1H-Benzimidazol-6-ylamino)-8-quinazolinyl]oxy]-cyclohexanol inhibits Traf2 and Nck-interacting protein kinase (TNIK). TNIK is involved with Canonical Wnt/b-catenin signalling, which has regulatory roles in maintaining intestinal stem cells and aberration in this pathway has been implicated in colorectal carcinogenesis. TNIK is a therapeutic […]