Drug Delivery

Catalogue Number:B200500Chemical Name:4-Benzothiazoleacetic AcidCAS Number:208117-17-3Molecular Formula:C₉H₇NO₂SMolecular Weight:193.22Category:Building Blocks; Miscellaneous;Applications:4-Benzothiazoleacetic Acid is used in the synthesis of acyloxyalkyl and aspartyl amidooxyalkyl ketones with ICE-inhibiting activities.References:Galatsis, P., et al.: Bioorg. Med. Chem. Lett., 20, 5089 (2010)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will […]

Catalogue Number:B200095Chemical Name:Berberrubine ChlorideSynonyms:9-Berberoline Chloride; 9-Demethoxy-9-hydroxyberberinium Chloride; Berberrubine Chloride; Beroline Chloride;CAS Number:15401-69-1Alternate CAS #Free Base: 17388-19-1Molecular Formula:C₁₉H₁₆ClNO₄Appearance:White to Dark Yellow SolidMelting Point:>145°C (dec.)Molecular Weight:357.79Storage:-20°CSolubility:DMSO (Slightly, Heated), Methanol (Slightly)StabilityHygroscopicCategory:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Berberrubine Chloride is a novel alkaloid with novel nitric-oxide donating activity. Antitumor and an antimicrobial agent.References:Chen, J. et al.: Eur. J. Med. Chem., 132, 173 […]

Catalogue Number:B200060Chemical Name:(S)-1,4-Benzodioxan-2-carboxypiperazineSynonyms:[(2S)-2,3-Dihydro-1,4-benzodioxin-2-yl]-1-piperazinyl-methanoneCAS Number:401941-54-6Molecular Formula:C₁₃H₁₆N₂O₃Appearance:White SolidMelting Point:129-132ºCMolecular Weight:248.28Storage:4°CSolubility:Chloroform (Slightly), Methanol (Slightly)Category:Standards; Chiral Molecules;Applications:(S)-1,4-Benzodioxan-2-carboxypiperazine is the key chiral intermediate for the synthesis of (S)-doxazosin (D537500, Mesylate salt), a selective a1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate.References:Fang, Q., et al.: Tetrahedron Asym., 12, 2169 (2001); Elliott, H.L., et al.: Brit. J. Clin. Pharmacol., 13, 699 […]

Catalogue Number:B200055Chemical Name:2-Bromo-1-[4-(trifluoromethoxy)phenyl]ethan-1-oneSynonyms:2-Bromo-1-(4-trifluoromethoxyphenyl)ethanone; 2-Bromo-4′-(trifluoromethoxy)acetophenone; 4-(Trifluoromethoxy)phenacyl bromideCAS Number:103962-10-3Molecular Formula:C₉H₆BrF₃O₂Appearance:White to Off-White SolidMelting Point:54 – 55°CMolecular Weight:283.04Storage:-20°C, Inert atmosphereSolubility:Chloroform (Sparingly), Methanol (Slightly)Category:Building Blocks; Miscellaneous;Applications:2-Bromo-1-[4-(trifluoromethoxy)phenyl]ethan-1-one is an intermediate used to prepare aminothiazoles as therapeutic leads for prion diseases. It is also used in the synthesis of pyrrolidino-tetrahydroisoquinolines as potent dual H3 antagonist and serotonin transporter inhibitors.References:Gallardo-Godoy, A., et […]

Catalogue Number:B200050Chemical Name:7-Benzothiazolecarboxylic AcidSynonyms:1,3-Benzothiazole-7-carboxylic AcidCAS Number:677304-83-5Molecular Formula:C₈H₅NO₂SAppearance:White SolidMelting Point:>300°CMolecular Weight:179.2Storage:4°CSolubility:Aqueous Base (Slightly), DMSO (Slightly), Methanol (Very Slightly)Category:Building Blocks; Miscellaneous;Applications:7-Benzothiazolecarboxylic Acid is an intermediate used in the synthesis of pyrazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1). It is also used to prepare aminofuro-pyridine derivatives as inhibitors of TAK1.References:Huynh, T., et al.: Bioorg. Med. Chem. […]

Catalogue Number:B200035Chemical Name:(6S,12bR)-6-(1,3-Benzodioxol-5-yl)-2,3,7,12b-tetrahydro-2-methyl-pyrazino[1′,2′:1,5]pyrrolo[3,4-b]quinoline-1,4,12(6H)-trioneCAS Number:531500-48-8Molecular Formula:C₂₂H₁₇N₃O₅Molecular Weight:403.39Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(6S,12bR)-6-(1,3-Benzodioxol-5-yl)-2,3,7,12b-tetrahydro-2-methyl-pyrazino[1′,2′:1,5]pyrrolo[3,4-b]quinoline-1,4,12(6H)-trione is tetracyclic pyrroloquinolone derivative and is known to be a potential phosphodiesterase 5 inhibitor.References:Jiang, W., et al.: Bioorg. Med. Chem., 12, 1505 (2004);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the […]

Catalogue Number:B200033Chemical Name:(6S,​12bS)​-6-​(1,​3-​Benzodioxol-​5-​yl)​-​2,​3,​7,​12b-​tetrahydro-​2-​methyl-​pyrazino[1′,​2′:1,​5]​pyrrolo[3,​4-​b]​quinoline-​1,​4,​12(6H)​-​trioneSynonyms:(6S,12bS)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3-dihydropyrazino[1′,2′:1,5]pyrrolo[3,4-b]quinoline-1,4,12(6H,7H,12bH)-trioneCAS Number:531500-47-7Molecular Formula:C₂₂H₁₇N₃O₅Appearance:Brown SolidMolecular Weight:403.39Solubility:Dichloromethane (Partially)Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(6S,​12bS)​-6-​(1,​3-​Benzodioxol-​5-​yl)​-​2,​3,​7,​12b-​tetrahydro-​2-​methyl-​pyrazino[1′,​2′:1,​5]​pyrrolo[3,​4-​b]​quinoline-​1,​4,​12(6H)​-​trione is a tetracyclic pyrroloquinolone derivative.References:Jiang, W.Q., et al.: Bioog. Med. Chem., 12, 1505 (2004);To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes […]

Catalogue Number:B200025Chemical Name:(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl EsterCAS Number:171596-44-4Molecular Formula:C₂₀H₁₈N₂O₄Appearance:White to Off-White SolidMelting Point:187-189°CMolecular Weight:350.37Storage:4°CSolubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)Category:Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Tadalafil (T004500) derivative. Used in the preparation of pyrazinopyridoindole derivatives for their PDE5 inhibitory activity.References:Beghyn, T. et al.: Bioorgan. Med. Chem. Lett. 17, 789(2007)To ensure the stability of our […]

Catalogue Number:B200020Chemical Name:(1S,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl EsterSynonyms:(1S-cis)-1-(1,3-benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl EsterCAS Number:171596-43-3Molecular Formula:C₂₀H₁₈N₂O₄Appearance:Pale Yellow SolidMelting Point:>90°C (dec.)Molecular Weight:350.37Storage:4°CSolubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)Category:Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Tadalafil (T004500) derivative. Used in the preparation of pyrazinopyridoindole derivatives for their PDE5 inhibitory activity.References:Beghyn, T. et al.: Bioorgan. Med. Chem. Lett. 17, 789(2007)To ensure the […]

Catalogue Number:B200005Chemical Name:(1S,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl EsterCAS Number:629652-42-2Molecular Formula:C₂₂H₁₉ClN₂O₅Appearance:Light Yellow SolidMelting Point:208-210ºCMolecular Weight:426.85Storage:4°CSolubility:DMSO, MethanolCategory:Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Tadalafil (T004500) derivative.References:Beghyn, T. et al.: Bioorgan. Med. Chem. Lett. 17, 789(2007)To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be […]