Drug Delivery

Catalogue Number:B382095Chemical Name:BictegravirSynonyms:GS-9883; (2R,5S,13aR)-2,3,4,5,7,9,13,13a-octahydro-8-hydroxy-7,9-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-2,5-Methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamideCAS Number:1611493-60-7Molecular Formula:C₂₁H₁₈F₃N₃O₅Appearance:White to Off-White SolidMelting Point:>130°C (dec.)Molecular Weight:449.38Storage:-20°CSolubility:DMSO (Slightly), Methanol (Slightly)Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;Applications:Bictegravir, is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM.References:Tsiang M. et al.: Antimicrob Agents Chemother. 2016 Nov 21;60(12):7086-7097;To ensure the stability of our products, the efficient express delivery service will be […]

Catalogue Number:B382055Chemical Name:Bicalutamide SulfoxideSynonyms:USP Bicalutamide Related Compound A; (N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfinyl]-2-hydroxy-2-methyl-propanamide);Impurity:Bicalutamide USP Related Compound ACAS Number:945419-64-7Molecular Formula:C₁₈H₁₄F₄N₂O₃SAppearance:White to Off-White SolidMelting Point:127-130°CMolecular Weight:414.37Storage:4°CSolubility:Chloroform (Slightly, Sonicated), Methanol (Slightly)Category:Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Bicalutamide Sulfoxide is a derivative of Bicalutamide (B382000), non-steroidal peripherally active antiandrogen. Used as an antiandrogen, antineoplastic (hormonal).References:Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, […]

Catalogue Number:B382040Chemical Name:Bicalutamide SulfideSynonyms:(+/-)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methyl-propanamide; (R,S)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide; Bicalutamide EP Impurity JImpurity:Bicalutamide EP Impurity JCAS Number:90356-78-8Molecular Formula:C₁₈H₁₄F₄N₂O₂SAppearance:White SolidMelting Point:109-111°CMolecular Weight:398.37Storage:4°CSolubility:Chloroform (Slightly), Methanol (Slightly)Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Bicalutamide Sulfide (Bicalutamide EP Impurity J) is a Bicalutamide intermediate.References:Tucker, H., et al.: J. Med. Chem., 31, 954 (1988),To ensure the stability of our products, the efficient express delivery service will be […]

Catalogue Number:B382015Chemical Name:Bicalutamide O-β-D-Glucuronide >80%Synonyms:2-[[4-Cyano-3-(trifluoromethyl)phenyl]amino]-1-[[(4-fluorophenyl)sulfonyl]methyl]-1-methyl-2-oxoethyl β-D-Glucopyranosiduronic Acid; Bicalutamide Glucuronide; Casodex Glucuronide;CAS Number:151262-59-8Molecular Formula:C₂₄H₂₂F₄N₂O₁₀SAppearance:White to Off-White SolidMolecular Weight:606.5Storage:-20°C, HygroscopicSolubility:DMSO (Slightly), Water (Slightly)StabilityHygroscopicCategory:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:A metabolite of the non-steroidal peripherally active antiandrogen Bicalutamide (B382000).References:McKillop, D. et al.: Xenobiot., 23, 1241 (1993); McKillop, D. et al.: Xenobiotica, 25, 623 (1995);To ensure the stability of our products, the […]

Catalogue Number:B382012Chemical Name:(S)-Bicalutamide-D4Synonyms:(2S)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl-D4)sulfonyl]-2-hydroxy-2-methylpropanamide; (S)-Casodex-D4; (S)-N-(4-Cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl-2,3,5,6-D4)sulfonyl)-2-hydroxy-2-methylpropanamideCAS Number:1217769-79-3Alternate CAS #113299-38-0Molecular Formula:C₁₈H₁₀D₄F₄N₂O₄SAppearance:Off-White Crystalline SolidMelting Point:175-179°CMolecular Weight:434.4Storage:-20°CSolubility:Acetone, Ethyl AcetateCategory:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(S)-Bicalutamide-D4 is a labelled analog of (S)-Bicalutamide (CAT# B382010), which is an isomer of Bicalutamide (CAT# B382000), a non-​steroidal anti-​androgen used for the treatment of prostate cancer.References:James, K. D., et al.: Tetrahedron, 58, 5905 (2002); […]

Catalogue Number:B382010Chemical Name:(S)-BicalutamideSynonyms:(2S)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide; (S)-Casodex;CAS Number:113299-38-0Molecular Formula:C₁₈H₁₄F₄N₂O₄SAppearance:White to Off-White SolidMelting Point:175-179°CMolecular Weight:430.37Storage:-20°CSolubility:Acetone (Slightly), Acetonitrile (Slightly), Ethyl Acetate (Slightly), MethanolCategory:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(S)-Enantiomer of Bicalutamide. Used as an antiandrogen, antineoplastic (hormonal).References:Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: […]

Catalogue Number:B382007Chemical Name:(R)-Bicalutamide-D4Synonyms:(2R)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl-d4)sulfonyl]-2-hydroxy-2-methylpropanamide; (R)-Casodex-d4;CAS Number:1217826-87-3Molecular Formula:C₁₈H₁₀D₄F₄N₂O₄SAppearance:Off-White Crystalline SolidMelting Point:178-181°CMolecular Weight:434.4Solubility:Ethyl AcetateCategory:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Labelled (R)-enantiomer of Bicalutamide. Used as an antiandrogen, antineoplastic (hormonal).References:Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, […]

Catalogue Number:B382005Chemical Name:(R)-BicalutamideSynonyms:(2R)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide; (R)-Casodex;CAS Number:113299-40-4Molecular Formula:C₁₈H₁₄F₄N₂O₄SAppearance:White to Off-White SolidMelting Point:178-181°CMolecular Weight:430.37Storage:-20°CSolubility:Acetone (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;Applications:(R)-Enantiomer of Bicalutamide. Used as an antiandrogen, antineoplastic (hormonal).References:Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. […]

Catalogue Number:B382002Chemical Name:Bicalutamide-d4Synonyms:N-[4-Cyano-3-trifluoromethyl)phenyl]- 3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide-d4; ICI-176334-d4; Casodex-d4;CAS Number:1185035-71-5Alternate CAS #unlabelled: 90357-06-5Molecular Formula:C₁₈H₁₀D₄F₄N₂O₄SAppearance:White to Off-White SolidMelting Point:190-1920CMolecular Weight:434.4Storage:-20°CSolubility:Chloroform (Slightly), Methanol (Slightly)Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Used as an antiandrogen, antineoplastic (hormonal). (94%d4References:Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: […]

Catalogue Number:B382000Chemical Name:BicalutamideSynonyms:N-[4-Cyano-3-trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-CAS Number:90357-06-5Molecular Formula:C₁₈H₁₄F₄N₂O₄SAppearance:White to Off-White SolidMelting Point:191-193°CMolecular Weight:430.37Storage:-20°CSolubility:Acetone (Slightly), Methanol (Slightly)Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Non-steroidal peripherally active antiandrogen. Used as an antiandrogen, antineoplastic (hormonal)References:Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 […]